Market guide
United States
Schedule III Controlled Substance. Federal law permits telemedicine prescribing of Schedule III substances with a valid patient-provider relationship. However, state laws vary significantly. Some states require in-person visits before telemedicine TRT, while others allow fully remote treatment. The Ryan Haight Act was modified during the pandemic to allow telemedicine for controlled substances, but ongoing regulatory changes apply.
Avg monthly
$115-179
Providers
16 tracked
Telemedicine
Allowed
Oversight
DEA
Key facts
- ▸Testosterone is a Schedule III controlled substance
- ▸Telemedicine prescribing is federally permitted but state-regulated
- ▸Endocrine Society guidelines recommend diagnosis based on symptoms + low morning testosterone
- ▸Compounding pharmacies are a common medication source
- ▸Insurance coverage varies; many clinics are cash-pay
Diagnosis and oversight
Total testosterone < 300 ng/dL on two separate morning tests + clinical symptoms
Guidelines: Endocrine Society, American Urological Association (AUA)
Oversight: DEA, State Medical Boards, FDA
Tracked online providers in United States
Defy Medical
Established physician-led telehealth hormone clinic with personalized TRT, ancillary medications, and broad lab/medication coordination.
Hone Health
Large consumer telehealth platform for men’s hormone care with at-home/in-person labs, physician review, and tiered membership plans.
TRT Nation
TRT-focused telehealth provider with home delivery, straightforward testosterone/hCG positioning, and high public review visibility.
Alpha MD
Online men’s-health clinic offering TRT, HCG, and broader hormone treatment through telehealth.
PeterMD
Large online men’s hormone clinic positioning itself as an affordable North American telehealth provider for TRT and related optimization care.
FountainTRT
Online TRT brand focused on convenience, remote evaluation, and treatment coordination.
Male Excel
Men’s health and hormone optimization platform offering TRT-related care and broader wellness programs.
Blokes
Men’s health clinic brand commonly surfaced in online TRT comparisons, with hormone optimization and telehealth-style services.
Viking Alternative Medicine
Hormone and anti-aging clinic with online presence for testosterone optimization and related therapies.
Royal Medical Center
TRT clinic brand frequently referenced in online TRT comparisons; positioned around medically supervised testosterone treatment.
Evolve Telemed
Telemedicine hormone and wellness clinic commonly associated with TRT, peptides, and anti-aging protocols.
Marek Health
Health-optimization telehealth clinic frequently compared in TRT contexts, with lab-heavy and performance-health positioning.
Matrix Hormones
Conservative US medical clinic specializing in hormone replacement therapy with thorough diagnostic workup and physician-supervised treatment. Requires comprehensive lab work before prescribing.
Aspire Rejuvenation
US anti-aging and hormone optimization clinic offering testosterone replacement therapy, peptide therapy, and weight management. Physician-supervised with comprehensive lab monitoring.
Rise Men’s Health eTRT
US telehealth clinic specializing in TRT and men's health optimization. Evidence-based protocols with comprehensive lab analysis and physician consultations.
Maximus
Online men’s hormone optimization service focused on raising testosterone, commonly compared with TRT clinics but not always conventional testosterone replacement.