TRT + HCG Pharmacokinetics

Educational simulator • Validate decisions with labs and clinician guidance • Engine v21.0
How It Works API
Standard Model Standard

Inputs

Enhanced Compounds (TRT++) optional adjunct modeling

Mast is modeled mainly as symptom-support context with minimal aromatase impact.

Ester
Add HCG
Modeled as LH-like stimulation.
Scenarios

Schedule & summary

Peak T
Trough T
Avg T
Active Ester
Injection days (last 28d)

This tool is for visualization and discussion. Real serum levels vary by absorption, injection technique, lab timing, SHBG, BMI, and assay methods.

Testosterone curve

ng/dL

Shaded band shows an estimated model range (+/-15%) rather than a single deterministic line.

18%
1x

Estradiol (E2) simulation

Ref: —

Estradiol forecast: projected E2 trend over your latest dosing window with a +/-15% uncertainty band.

Peak E2
Avg E2
Phenotype
Activity
Aromatase activity

Genetics (simplified)

E2 tendency
CYP19 / conversion
SHBG tendency

Symptoms reference

non-diagnostic
  • Fluid retention, “puffy” look
  • Mood lability, irritability
  • Low libido/ED (in some)
  • Sensitive nipples
  • Higher BP / headaches

Symptoms overlap with prolactin, thyroid, sleep, dosing peaks, and anxiety. Labs and timing matter.

Ester profiles

half-life driven

Lab calibration (optional)

Use calibration in simulation
Calibration inactive
T factor: 1.00x E2 ratio: 0.050 Standard factors active

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PK estimation model based on population medians. Does not model endogenous shutdown, Free T, or individual enzymatic response. Never adjust prescription doses from this simulator alone.

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